Western NY State Tobacco-Free Programs: "Crazy driver"

Nice message, and delivered in a way that makes the point without being whiney (as so many PSA's and anti-smoking ads are)

Epuron: "Wind"

Okay, so this is tough to understand, between the webby sound, the accent, and the deep voice, but... bear with it, because the payoff at the end is just fantastic.

The "Crying Indian" pollution ad

This one was ubiqitous in the 70s -- as was litter along the nation's highways. Did it singlehandedly change America's litterbugs? Nah. But was it memorable and impactful as hell, and did it likely make a difference? Uh, yah.